Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.57 |
| ▸ | CCR3 | P51677 | 20/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180268 | 0.93 | HRH1 (0.59) | HRH1CCR3KCNH2 | |
| SCHEMBL180280 | 0.90 | HRH1 (0.71) | HRH1CCR3KCNH2 | |
| SCHEMBL180188 | 0.84 | HRH1 (0.81) | HRH1CCR3KCNH2 | |
| SCHEMBL14110513 | 0.82 | HRH1 (0.77) | HRH1CCR3KCNH2 | |
| SCHEMBL180197 | 0.82 | HRH1 (0.72) | HRH1CCR3KCNH2 | |
| SCHEMBL180275 | 0.81 | HRH1 (0.66) | HRH1CCR3KCNH2 | |
| SCHEMBL180186 | 0.81 | HRH1 (0.72) | HRH1CCR3KCNH2 | |
| SCHEMBL180078 | 0.80 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| SCHEMBL180367 | 0.80 | HRH1 (0.70) | HRH1CCR3KCNH2 | |
| SCHEMBL180098 | 0.80 | HRH1 (0.67) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402316-A1 | Piperidine derivatives | AstraZeneca AB (Publ) (SE) | 2012-01-04 | — | — | EP | disclosed |