Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 1.00 |
| ▸ | WDR77 | Q9BQA1 | 14/20 | 1.00 |
| ▸ | AHCY | P23526 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21413928 | 1.00 | PRMT5 (1.00) | PRMT5WDR77AHCY | |
| SCHEMBL18009839 | 1.00 | PRMT5 (1.00) | PRMT5WDR77AHCY | |
| SCHEMBL24625951 | 0.92 | PRMT5 (0.84) | PRMT5WDR77 | |
| SCHEMBL24478704 | 0.92 | PRMT5 (0.84) | PRMT5WDR77 | |
| SCHEMBL24625909 | 0.87 | PRMT5 (0.77) | PRMT5WDR77AHCY | |
| SCHEMBL18026153 | 0.86 | PRMT5 (0.76) | PRMT5WDR77 | |
| SCHEMBL18026117 | 0.86 | PRMT5 (0.76) | PRMT5WDR77 | |
| SCHEMBL24146403 | 0.85 | PRMT5 (0.75) | PRMT5WDR77 | |
| SCHEMBL30128123 | 0.85 | PRMT5 (0.75) | PRMT5WDR77 | |
| SCHEMBL7732757 | 0.85 | PRMT5 (0.74) | PRMT5WDR77AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262057-B1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3262057-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Inc (US) | 2018-01-03 | — | — | EP | disclosed |
| WO-2016135582-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2016-09-01 | — | — | WO | disclosed |