Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.76 |
| ▸ | PKD1 | P98161 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18039367 | 0.91 | MAP3K14 (0.79) | MAP3K14 | |
| SCHEMBL18055881 | 0.86 | MAP3K14 (0.83) | MAP3K14 | |
| SCHEMBL16532282 | 0.86 | MAP3K14 (1.00) | MAP3K14 | |
| SCHEMBL18055853 | 0.85 | MAP3K14 (0.70) | MAP3K14 | |
| SCHEMBL18039305 | 0.84 | MAP3K14 (0.82) | MAP3K14 | |
| SCHEMBL18039354 | 0.84 | MAP3K14 (0.76) | MAP3K14 | |
| SCHEMBL18039361 | 0.83 | MAP3K14 (0.78) | MAP3K14 | |
| SCHEMBL18039345 | 0.83 | MAP3K14 (0.78) | MAP3K14 | |
| SCHEMBL18039447 | 0.83 | MAP3K14 (0.77) | MAP3K14 | |
| SCHEMBL18055807 | 0.82 | MAP3K14 (0.66) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3262035-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2018-01-03 | — | — | EP | disclosed |
| WO-2016135163-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2016-09-01 | — | — | WO | disclosed |
| WO-2016135163-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2016-09-01 | — | — | WO | disclosed |