Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 14/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18072 | 0.99 | HPGD (0.46) | SLC5A2SLC5A1HPGDMEN1ALDH1A1 | |
| SCHEMBL17831 | 0.90 | SLC5A2 (0.43) | SLC5A2SLC5A1HPGDHTR2ASLC6A4 | |
| SCHEMBL23912 | 0.86 | SLC5A2 (0.38) | SLC5A2SLC5A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL17356 | 0.85 | SLC5A2 (0.38) | SLC5A2SLC5A1 | |
| SCHEMBL17334 | 0.83 | SLC5A2 (0.38) | SLC5A2SLC5A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL18499 | 0.83 | SLC5A2 (0.39) | SLC5A2SLC5A1SLC6A4 | |
| SCHEMBL18178 | 0.80 | SLC5A2 (0.39) | SLC5A2SLC5A1 | |
| SCHEMBL17483 | 0.80 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL29386304 | 0.79 | SLC5A2 (0.53) | SLC5A2SLC5A1ALDH1A1MAPT | |
| SCHEMBL38150 | 0.79 | SLC5A2 (0.53) | SLC5A2SLC5A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |