Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18040350 | 1.00 | CYP2D6 (0.41) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL17923208 | 1.00 | CYP2D6 (0.41) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL29182460 | 0.98 | CHRM2 (0.43) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL29182446 | 0.98 | CHRM2 (0.43) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL29182441 | 0.98 | CHRM2 (0.43) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL7839730 | 0.95 | MEN1 (0.46) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL9015291 | 0.95 | MEN1 (0.46) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL25338317 | 0.88 | MEN1 (0.38) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL20595815 | 0.88 | MEN1 (0.38) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL29182442 | 0.88 | MEN1 (0.38) | CYP2D6CHRM2CHRM1CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144241-A1 | THERAPEUTIC USE OF ISOMERIC FORMS OF 2-(4-CHLOROPHENYL)QUINOLIN-4-YL)(PIPERIDIN-2-YL)METHANOL | GLIONOVA AB (SE) | 2016-09-15 | — | — | WO | disclosed |
| EP-3064205-A1 | Therapeutic use of isomeric forms of 2-(4-chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol | Glionova AB (SE) | 2016-09-07 | — | — | EP | disclosed |