SCHEMBL18042240

SCHEMBL18042240

c1ccc2c(c1)[nH]c1ccc(-c3ccc4c5cccc6c7ccccc7n(c4c3)c65)cc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.43
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41
GABRA6 Q16445 1/20 0.41
GABRG1 Q8N1C3 1/20 0.41
GABRG3 Q99928 1/20 0.41
GABRQ Q9UN88 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GPR3 P46089 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26287764 0.93 AHR (0.44) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL17265129 0.90 AHR (0.47) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL16622105 0.90 AHR (0.39) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL26532148 0.89 CDK4 (0.39) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL23820553 0.86 AHR (0.41) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL17265130 0.85 AHR (0.46) AHRALDH1A1HSD17B10GPR3KIF11
SCHEMBL23823577 0.84 POLB (0.44) ALDH1A1GPR3KIF11KDM4EMEN1
SCHEMBL20068639 0.84 AHR (0.49) AHRALDH1A1HSD17B10GPR3KIF11
SCHEMBL20068635 0.84 AHR (0.49) AHRALDH1A1HSD17B10GPR3KIF11
SCHEMBL24161464 0.84 AHR (0.52) AHRGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12284913-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2025-04-22 US disclosed
US-20220115601-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2022-04-14 US disclosed
US-11245080-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-08 US disclosed
US-11245080-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-02-08 US disclosed
US-20200194688-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-06-18 US disclosed
US-20200194688-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORP (US) 2020-06-18 US disclosed
US-10686143-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-06-16 US disclosed
US-20160293853-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed
US-20160293853-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 US disclosed
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERAL DISPLAY CORPORATION (US) 2016-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12284913-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, JUND AHR 1725/4885GABRP 3984/4885GABRD 689/4885
US-20160260908-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, JUND AHR 980/4885GABRP 3010/4885GABRD 2623/4885
US-20200194688-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND AHR 1725/4885GABRP 3984/4885GABRD 689/4885
US-20220115601-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND AHR 1725/4885GABRP 3984/4885GABRD 689/4885
US-20160293853-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND AHR 1725/4885GABRP 3984/4885GABRD 689/4885
US-10686143-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, JUND AHR 980/4885GABRP 3010/4885GABRD 2623/4885
US-11245080-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, JUND AHR 1725/4885GABRP 3984/4885GABRD 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.