Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 1.00 |
| ▸ | FLT3 | P36888 | 5/20 | 0.77 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666605 | 1.00 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL16311120 | 0.94 | SYK (0.89) | SYKFLT3AURKB | |
| SCHEMBL14666556 | 0.89 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL18044072 | 0.89 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL14666638 | 0.87 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL14666628 | 0.85 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL18044056 | 0.85 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL14666639 | 0.84 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL18044030 | 0.84 | SYK (1.00) | SYKFLT3AURKB | |
| SCHEMBL14659538 | 0.83 | SYK (1.00) | SYKFLT3AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736886-B1 | SUBSTITUTED QUINOLINES AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2016-09-14 | — | — | EP | disclosed |