Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039823 | 0.90 | GUCY1A1 (0.57) | GUCY1A1GUCY1B1 | |
| SCHEMBL18044284 | 0.88 | GUCY1A1 (0.54) | GUCY1A1GUCY1B1 | |
| SCHEMBL1782759 | 0.87 | GUCY1A1 (0.58) | GUCY1A1GUCY1B1 | |
| SCHEMBL3041587 | 0.86 | GUCY1A1 (0.54) | GUCY1A1GUCY1B1 | |
| SCHEMBL1781270 | 0.86 | GUCY1A1 (0.56) | GUCY1A1GUCY1B1 | |
| SCHEMBL3031789 | 0.85 | GUCY1A1 (0.57) | GUCY1A1GUCY1B1 | |
| SCHEMBL16835708 | 0.85 | GUCY1A1 (0.57) | GUCY1A1GUCY1B1 | |
| SCHEMBL3040871 | 0.85 | GUCY1A1 (0.62) | GUCY1A1GUCY1B1 | |
| SCHEMBL3030596 | 0.85 | GUCY1A1 (0.58) | GUCY1A1GUCY1B1 | |
| SCHEMBL18044287 | 0.84 | GUCY1A1 (0.55) | GUCY1A1GUCY1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401265-B1 | DERIVATIVES OF 1-PYRI(MID)IN-2-YL-PYRAZOLE-4-CARBOXYLIC ACID WHICH ARE USEFUL FOR THERAPY OR PROPHYLAXIS OF CARDIOVASCULAR DISEASES | MERCK SHARP & DOHME (US) | 2016-09-14 | — | — | EP | disclosed |