Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrocinnamyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrocinnamyl Alcohol SCHEMBL28212065 | 0.93 | TDP1 (0.58) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL28172060 | 0.93 | TDP1 (0.58) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL1868196 | 0.93 | TDP1 (0.70) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL27804855 | 0.93 | TDP1 (0.70) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL1922 | 0.93 | TDP1 (0.70) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL27451293 | 0.93 | TDP1 (0.70) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL27568691 | 0.91 | TDP1 (0.56) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL1325126 | 0.90 | TDP1 (0.67) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL9615638 | 0.90 | TDP1 (0.67) | TDP1LTA4HEPHX2ADRA1ASLC6A3 | |
| Hydrocinnamyl Alcohol SCHEMBL19667853 | 0.90 | TDP1 (0.67) | TDP1LTA4HEPHX2ADRA1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2505060-B1 | New disinfectant mixture of alcool and glycerol ether for the control of mycobacteria | AIR LIQUIDE SANTE INT (FR) | 2016-09-14 | — | — | EP | claimed |
| US-12006385-B2 | Comb polymer | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2024-06-11 | — | — | US | disclosed |
| CN-113265055-B | Comb polymers | 原子能与替代能源委员会 | 2022-12-30 | — | — | CN | disclosed |
| US-20210296699-A1 | SOLID POLYMER ELECTROLYTE BASED ON A COMB POLYMER | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2021-09-23 | — | — | US | disclosed |
| US-20210253760-A1 | COMB POLYMER | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2021-08-19 | — | — | US | disclosed |
| CN-113270638-A | Solid polymer electrolytes based on comb polymers | 原子能与替代能源委员会 | 2021-08-17 | — | — | CN | disclosed |
| CN-113265055-A | Comb polymers | 原子能与替代能源委员会 | 2021-08-17 | — | — | CN | disclosed |