Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 6/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 5/20 | 0.40 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 12/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18045184 | 0.89 | AXL (0.44) | TYRO3AXLMERTKMETNEK7 | |
| SCHEMBL18045156 | 0.88 | AXL (0.46) | AXLMERTKMETNEK7FLT3 | |
| SCHEMBL18044731 | 0.87 | FLT3 (0.42) | TYRO3AXLMERTKMETNEK7 | |
| SCHEMBL16709400 | 0.85 | MERTK (0.53) | TYRO3AXLMERTKMETFLT3 | |
| SCHEMBL18044634 | 0.84 | AXL (0.52) | TYRO3AXLMERTKMETFLT3 | |
| SCHEMBL18045186 | 0.83 | AXL (0.45) | AXLMERTKMETFLT3 | |
| SCHEMBL18044745 | 0.83 | AXL (0.47) | TYRO3AXLMERTKMETNEK7 | |
| SCHEMBL18044544 | 0.82 | AXL (0.51) | TYRO3AXLMERTKMETFLT3 | |
| SCHEMBL18045175 | 0.82 | AXL (0.49) | AXLMERTKMETFLT3 | |
| SCHEMBL18045160 | 0.81 | NEK7 (0.44) | AXLMERTKNEK7FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067356-A1 | PYRROLO PYRIMIDINE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2016-09-14 | — | — | EP | disclosed |