Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.73 |
| ▸ | CCNK | O75909 | 10/20 | 0.73 |
| ▸ | CDK12 | Q9NYV4 | 10/20 | 0.73 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.73 |
| ▸ | CDK9 | P50750 | 8/20 | 0.73 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.73 |
| ▸ | CDK7 | P50613 | 8/20 | 0.64 |
| ▸ | CCNH | P51946 | 7/20 | 0.64 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.64 |
| ▸ | MAPK8 | P45983 | 10/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 10/20 | 0.63 |
| ▸ | JUN | P05412 | 9/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665619 | 1.00 | CDK2 (0.73) | CDK2CCNKCDK12CCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL16655279 | 0.99 | CDK2 (0.71) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL18074109 | 0.86 | CDK2 (0.69) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL16655002 | 0.86 | CDK2 (0.69) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL16655000 | 0.86 | CDK2 (0.69) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL16654998 | 0.86 | CDK2 (0.69) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL16655050 | 0.86 | CDK2 (0.69) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL21027454 | 0.86 | CDK2 (0.89) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL16665609 | 0.85 | CDK7 (0.69) | CDK2CCNKCDK12CCNT1CDK9 | |
| SCHEMBL18074062 | 0.85 | CDK7 (0.69) | CDK2CCNKCDK12CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264552-A1 | HETEROMAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLFERATIVE DISEASES | SYROS PHARMACEUTICALS INC (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264552-A1 | HETEROMAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLFERATIVE DISEASES | CDK7, CDK6, CDK3 | CDK2 4/4885CCNK 9/4885CDK12 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.