Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 18/20 | 0.57 |
| ▸ | VEGFA | P15692 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18067992 | 1.00 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL18067991 | 1.00 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL19872259 | 1.00 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL19872188 | 0.92 | EPAS1 (0.56) | EPAS1VEGFA | |
| SCHEMBL18688700 | 0.91 | EPAS1 (0.53) | EPAS1VEGFA | |
| SCHEMBL19870952 | 0.90 | EPAS1 (0.59) | EPAS1VEGFA | |
| SCHEMBL19870950 | 0.88 | EPAS1 (0.55) | EPAS1VEGFA | |
| SCHEMBL20253166 | 0.88 | EPAS1 (0.45) | EPAS1VEGFA | |
| SCHEMBL19870911 | 0.88 | EPAS1 (0.57) | EPAS1VEGFA | |
| SCHEMBL19870906 | 0.88 | EPAS1 (0.57) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144825-A1 | AROMATIC COMPOUNDS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | WO | disclosed |