Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071000 | 1.00 | KDR (0.46) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18070998 | 1.00 | KDR (0.46) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18070882 | 0.88 | KDR (0.61) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18070943 | 0.88 | KDR (0.61) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18048930 | 0.88 | KDR (0.61) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18070885 | 0.88 | KDR (0.61) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18070976 | 0.88 | KDR (0.61) | KDRMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL18070977 | 0.87 | USP30 (0.39) | KMT2ATRPV1ALDH1A1HPGDCLK2 | |
| SCHEMBL18049022 | 0.87 | USP30 (0.39) | KMT2ATRPV1ALDH1A1HPGDCLK2 | |
| SCHEMBL18070934 | 0.87 | USP30 (0.39) | KMT2ATRPV1ALDH1A1HPGDCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | claimed |
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |