SCHEMBL18050

SCHEMBL18050

C[Si](C)(C)O[Si](C)(C)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
IDO1 P14902 2/20 0.41
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
ATM Q13315 1/20 0.39
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
KCNH2 Q12809 1/20 0.38
TSHR P16473 1/20 0.37
AOC3 Q16853 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4868417 0.91 TDP1 (0.46) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL7063056 0.90 TDP1 (0.39) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL18979042 0.88 IDO1 (0.47) IDO1HTR2AKCNH2AOC3
SCHEMBL20382909 0.88 TDP1 (0.43) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL20365397 0.86 TDP1 (0.41) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL21369187 0.86 TDP1 (0.41) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL18389767 0.83 TDP1 (0.43) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL738091 0.83 TDP1 (0.43) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL10535412 0.82 TDP1 (0.39) TDP1IDO1ALDH1A1HPGDALOX15
SCHEMBL17753735 0.82 CYP1A2 (0.43) IDO1ALDH1A1ALOX15TAAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1592603-A Water-in-oil emulsion compositions comprising polyalkylene glycol styling agents PROCTER & GAMBLE (US) 2005-03-09 CN claimed
EP-1309306-A2 WATER-IN-OIL EMULSION COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL STYLING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2003-05-14 EP claimed
WO-2002011684-A2 WATER-IN-OIL EMULSION COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL STYLING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2002-02-14 WO claimed
US-6300027-B1 Low surface energy photoreceptors XEROX CORPORATION 2001-10-09 US claimed
JP-2001507372-A 2001-06-05 JP claimed
CN-1261776-A Personal care compositions containing grafted polymers PROCTER & GAMBLE (US) 2000-08-02 CN claimed
EP-0977540-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP claimed
WO-1998051261-A1 PERSONAL CARE COMPOSITIONS CONTAINING GRAFT POLYMERS THE PROCTER & GAMBLE COMPANY (US) 1998-11-19 WO claimed
EP-0531328-A4 LIQUID ANTIPERSPIRANT COMPOSITIONS 1993-04-21 EP claimed
EP-0531337-A4 LIQUID ANTIPERSPIRANT COMPOSITIONS 1993-04-14 EP claimed
EP-0531337-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-03-17 EP claimed
EP-0531328-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-03-17 EP claimed
US-5095086-A Polysesquisiloxanes GENERAL ELECTRIC COMPANY (US) 1992-03-10 US claimed
EP-0470442-A2 Improved scuff-masking coatings for glass articles GENERAL ELECTRIC COMPANY (US) 1992-02-12 EP claimed
WO-1991018586-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1991-12-12 WO claimed
WO-1991018587-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1991-12-12 WO claimed
US-20250000778-A1 CHELANT AND CYCLODEXTRIN COMPOSITIONS COTY INC. 2025-01-02 US disclosed
EP-3184172-B1 HYDROSILYLATION IRON CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-09-04 EP disclosed
EP-0412705-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412710-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed