Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10008085 | 0.89 | — | — | |
| SCHEMBL10008081 | 0.89 | — | — | |
| SCHEMBL10006733 | 0.84 | — | — | |
| SCHEMBL10006731 | 0.84 | — | — | |
| SCHEMBL18720565 | 0.82 | — | — | |
| SCHEMBL18052010 | 0.81 | CDC7 (0.49) | JAK3 | |
| SCHEMBL28333089 | 0.81 | GSK3A (0.54) | — | |
| SCHEMBL28333172 | 0.81 | GSK3A (0.54) | — | |
| SCHEMBL28333085 | 0.81 | GSK3A (0.54) | — | |
| SCHEMBL10007054 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141252-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | Vertex Pharmaceuticals Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2442809-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2016-08-31 | — | — | EP | disclosed |