Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172397 | 0.79 | CHEK1 (0.50) | CHEK1CHEK2 | |
| SCHEMBL617322 | 0.78 | CHEK1 (0.49) | CHEK1CHEK2 | |
| SCHEMBL617141 | 0.78 | CHEK1 (0.69) | CHEK1CHEK2 | |
| SCHEMBL617305 | 0.75 | CHEK1 (0.51) | CHEK1CHEK2 | |
| SCHEMBL618324 | 0.74 | CHEK1 (0.68) | CHEK1CHEK2 | |
| SCHEMBL10217801 | 0.73 | CHEK1 (0.49) | CHEK1CHEK2 | |
| SCHEMBL28837308 | 0.72 | CHEK1 (0.48) | CHEK1CHEK2 | |
| SCHEMBL617518 | 0.72 | CHEK1 (0.72) | CHEK1CHEK2 | |
| SCHEMBL28837302 | 0.71 | CHEK1 (0.48) | CHEK1CHEK2 | |
| SCHEMBL16187941 | 0.70 | CHEK1 (0.70) | CHEK1CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197874-B1 | PYRAZIN-2-YL-PYRIDIN-2-YL-AMINE AND PYRAZIN-2-YL-PYRIMIDIN-4-YL-AMINE COMPOUNDS AND THEIR USE | CANCER REC TECH LTD (GB) | 2016-08-31 | — | — | EP | disclosed |