⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803958 | 0.85 | — | — | |
| SCHEMBL14964575 | 0.82 | — | — | |
| SCHEMBL14964624 | 0.82 | — | — | |
| SCHEMBL14964655 | 0.82 | — | — | |
| SCHEMBL12621538 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL9786005 | 0.69 | — | — | |
| SCHEMBL1803936 | 0.67 | — | — | |
| SCHEMBL1801684 | 0.64 | — | — | |
| SCHEMBL3849656 | 0.62 | — | — | |
| SCHEMBL3842315 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2701696-A2 | IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2701697-A2 | OXIDATIVE RETINAL DISEASES | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2701698-A2 | DISORDERS IMPLICATING PUFA OXIDATION | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2701695-A2 | NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012148926-A2 | NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012148927-A2 | IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012148930-A2 | OXIDATIVE RETINAL DISEASES | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012148929-A2 | DISORDERS IMPLICATING PUFA OXIDATION | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-2493296-A1 | ALLEVIATING OXIDATIVE STRESS DISORDERS WITH PUFA DERIVATIVES | Retrotope, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053870-A1 | ALLEVIATING OXIDATIVE STRESS DISORDERS WITH PUFA DERIVATIVES | RETROTOPE, INC. (US) | 2011-05-05 | — | — | WO | disclosed |