SCHEMBL1805487

SCHEMBL1805487

Cc1cc2c(c(=O)o1)C=C1CC[C@H](C(C)CO)C[C@@H]1O2

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 5/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16683901 0.89 SOAT1 (0.65) SOAT1
SCHEMBL12620884 0.89 SOAT1 (0.65) SOAT1
SCHEMBL12620900 0.87 SOAT1 (0.60) SOAT1
SCHEMBL12620912 0.87 SOAT1 (0.60) SOAT1
SCHEMBL12620825 0.85 SOAT1 (0.60) SOAT1
SCHEMBL12620823 0.84 SOAT1 (0.53) SOAT1
SCHEMBL7654433 0.83 SOAT1 (0.60) SOAT1
SCHEMBL12653722 0.82 SOAT1 (0.55) SOAT1
SCHEMBL19235665 0.81 SOAT1 (1.00) SOAT1
SCHEMBL12620914 0.80 SOAT1 (0.48) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935726-B1 Tricyclic pyrones KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-05-03 US disclosed
US-7935726-B1 Tricyclic pyrones KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-05-03 US disclosed
US-7935726-B1 Tricyclic pyrones KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2011-05-03 US disclosed
US-6916824-B1 Methods of treating cataracts and diabetic retinopathy with tricyclic pyrones KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2005-07-12 US disclosed
US-6384045-B1 TREATMENT OF ALZHEIMER'S DISEASE AND ANTICANCER AGENTS KANSAS STATE UNIVERSITY RESEARCH FOUNDATION 2002-05-07 US disclosed