Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.72 |
| ▸ | WDR77 | Q9BQA1 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18056012 | 0.91 | PRMT5 (0.75) | PRMT5WDR77 | |
| SCHEMBL21391714 | 0.89 | PRMT5 (0.84) | PRMT5WDR77 | |
| SCHEMBL21413921 | 0.89 | PRMT5 (0.84) | PRMT5WDR77 | |
| SCHEMBL18026204 | 0.89 | PRMT5 (0.84) | PRMT5WDR77 | |
| SCHEMBL18056011 | 0.87 | PRMT5 (0.70) | PRMT5WDR77 | |
| SCHEMBL18055941 | 0.86 | PRMT5 (0.69) | PRMT5WDR77 | |
| SCHEMBL18056054 | 0.86 | PRMT5 (0.74) | PRMT5WDR77 | |
| SCHEMBL19696633 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL18205102 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL18056014 | 0.86 | PRMT5 (0.74) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016135582-A1 | SUBSTITUTED NUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2016-09-01 | — | — | WO | disclosed |