Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.59 |
| ▸ | HRH1 | P35367 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805603 | 1.00 | HTR2B (0.59) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1806055 | 0.99 | HTR2B (0.58) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1806054 | 0.99 | HTR2B (0.58) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL656135 | 0.86 | HTR2B (0.42) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL656134 | 0.86 | HTR2B (0.42) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL1803063 | 0.85 | HTR2B (0.41) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL1803062 | 0.85 | HTR2B (0.41) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL1804621 | 0.84 | HTR2B (0.47) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL1804623 | 0.84 | HTR2B (0.47) | HTR2BHRH1KCNH2ALDH1A1LMNA | |
| SCHEMBL9130636 | 0.84 | HTR2B (0.69) | HTR2BHRH1KCNH2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2319840-B1 | AMINOPROPYLIDENE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2015-12-16 | — | — | EP | disclosed |
| US-8653285-B2 | Aminopropylidene derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2319840-A1 | AMINOPROPYLIDENE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2011-05-11 | — | — | EP | disclosed |