Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036980 | 0.86 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL12036903 | 0.76 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL12038764 | 0.75 | IRAK4 (0.45) | IRAK4 | |
| SCHEMBL12038355 | 0.74 | IRAK4 (0.44) | IRAK4 | |
| SCHEMBL12038338 | 0.74 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL12038538 | 0.74 | IRAK4 (0.31) | IRAK4 | |
| SCHEMBL12058101 | 0.74 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL12038029 | 0.74 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL12038032 | 0.74 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL13493456 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9433621-B2 | Substituted pyridine and pyrimidine derivatives and their use in treating viral infections | MERCK SHARP & DOHME CORP. (US) | 2016-09-06 | — | — | US | disclosed |
| US-9433621-B2 | Substituted pyridine and pyrimidine derivatives and their use in treating viral infections | MERCK SHARP & DOHME CORP. (US) | 2016-09-06 | — | — | US | disclosed |