Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048974 | 1.00 | EGLN1 (0.51) | EGLN1GRM4KMT2AHTTTSHR | |
| SCHEMBL18070950 | 1.00 | EGLN1 (0.51) | EGLN1GRM4KMT2AHTTTSHR | |
| SCHEMBL18070944 | 0.98 | EGLN1 (0.51) | EGLN1GRM4KMT2AHTTTSHR | |
| SCHEMBL18070982 | 0.98 | EGLN1 (0.51) | EGLN1GRM4KMT2AHTTTSHR | |
| SCHEMBL18070932 | 0.90 | KDR (0.49) | EGLN1KMT2AHTTL3MBTL1KDR | |
| SCHEMBL18070997 | 0.90 | KDR (0.49) | EGLN1KMT2AHTTL3MBTL1KDR | |
| SCHEMBL18070897 | 0.88 | KMT2A (0.47) | EGLN1GRM4KMT2AHTTTSHR | |
| SCHEMBL18070999 | 0.88 | KMT2A (0.47) | EGLN1GRM4KMT2AHTTTSHR | |
| SCHEMBL18070984 | 0.88 | EGLN1 (0.48) | EGLN1KMT2AHTTL3MBTL1KDR | |
| SCHEMBL18070989 | 0.88 | EGLN1 (0.48) | EGLN1KMT2AHTTL3MBTL1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |