Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CRHR1 | P34998 | 6/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048940 | 1.00 | KDR (0.54) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18070919 | 0.88 | KDR (0.63) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18070971 | 0.88 | KDR (0.63) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18048948 | 0.88 | KDR (0.63) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18070941 | 0.85 | KDR (0.52) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18048990 | 0.85 | KDR (0.52) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18070948 | 0.85 | KDR (0.52) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18048947 | 0.84 | KDR (0.53) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18070979 | 0.84 | KDR (0.53) | KDRRXFP1MEN1KMT2ALMNA | |
| SCHEMBL18070986 | 0.83 | KDR (0.48) | KDRRXFP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |