Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048934 | 0.89 | KDR (0.57) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18049039 | 0.87 | KDR (0.59) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18049841 | 0.86 | KDR (0.58) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18070891 | 0.85 | KDR (0.57) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18048967 | 0.84 | KDR (0.64) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18048926 | 0.82 | KDR (0.62) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18070875 | 0.81 | KDR (0.57) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18070871 | 0.81 | KDR (0.57) | KDREGLN1PTGS1SMN1; SMN2TRPV1 | |
| SCHEMBL18070967 | 0.79 | KDR (0.60) | KDREGLN1MEN1ALDH1A1MAPT | |
| SCHEMBL18071003 | 0.78 | KDR (0.66) | KDREGLN1PTGS1SMN1; SMN2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016144797-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |
| WO-2016144792-A1 | ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR ALLOSTERIC MODULATORS, THEIR DERIVATIVES AND USES THEREOF | ALPHARMAGEN, LLC (US) | 2016-09-15 | — | — | WO | disclosed |