Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350355 | 0.81 | — | — | |
| SCHEMBL372593 | 0.80 | TSHR (0.60) | MEN1KMT2APRMT1ALDH1A1ADRA1A | |
| SCHEMBL11811606 | 0.80 | TSHR (0.60) | MEN1KMT2APRMT1ALDH1A1ADRA1A | |
| SCHEMBL517606 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL25293705 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL25288050 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL699936 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL727151 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL10536662 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL25293609 | 0.78 | KMT2A (0.52) | SOAT1MEN1FAAHTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264968-A1 | MODIFIED iRNA AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2016-09-15 | — | — | US | disclosed |