Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.66 |
| ▸ | MAX | P61244 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934451 | 0.91 | MYC (0.72) | MYCMAXALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18070703 | 0.86 | MYC (0.62) | MYCMAXALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17927376 | 0.84 | MYC (0.76) | MYCMAXALDH1A1MAPTPDE4A | |
| SCHEMBL17927411 | 0.84 | MYC (0.72) | MYCMAXALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16810362 | 0.81 | MYC (0.82) | MYCMAXMAPTPDE4APDE4D | |
| SCHEMBL17927298 | 0.81 | MYC (0.71) | MYCMAXALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16810386 | 0.81 | MYC (0.72) | MYCMAXALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17927341 | 0.81 | MYC (0.70) | MYCMAXALDH1A1MAPTMEN1 | |
| SCHEMBL17927346 | 0.81 | MYC (0.70) | MYCMAXALDH1A1MAPTMEN1 | |
| SCHEMBL16792502 | 0.80 | MYC (1.00) | MYCMAXALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | SORRENTO THERAPEUTICS, INC. | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | MYC, MYCBP, MYCBP2 | MYC 1/4885MAX 42/4885ALDH1A1 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.