Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.67 |
| ▸ | CCNH | P51946 | 15/20 | 0.67 |
| ▸ | CCNK | O75909 | 13/20 | 0.67 |
| ▸ | CDK12 | Q9NYV4 | 13/20 | 0.67 |
| ▸ | CDK9 | P50750 | 12/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.67 |
| ▸ | MNAT1 | P51948 | 7/20 | 0.67 |
| ▸ | CDK13 | Q14004 | 9/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.53 |
| ▸ | CDK2 | P24941 | 7/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.52 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21397338 | 1.00 | CDK7 (0.67) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL18047427 | 1.00 | CDK7 (0.67) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL18047428 | 1.00 | CDK7 (0.67) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL18047410 | 1.00 | CDK7 (0.67) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL18047409 | 1.00 | CDK7 (0.67) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL16665598 | 0.91 | CDK7 (0.56) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL16654911 | 0.86 | CCNK (0.68) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL16654909 | 0.86 | CCNK (0.68) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL18047431 | 0.85 | CDK7 (0.68) | CDK7CCNHCCNKCDK12CDK9 | |
| SCHEMBL21397365 | 0.85 | CDK7 (0.68) | CDK7CCNHCCNKCDK12CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264552-A1 | HETEROMAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLFERATIVE DISEASES | SYROS PHARMACEUTICALS INC (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264552-A1 | HETEROMAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLFERATIVE DISEASES | CDK7, CDK6, CDK3 | CDK7 1/4885CCNH 32/4885CCNK 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.