⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074264 | 1.00 | — | — | |
| SCHEMBL18074271 | 0.89 | — | — | |
| SCHEMBL18074270 | 0.89 | — | — | |
| SCHEMBL18074266 | 0.79 | GRIN2C (0.75) | — | |
| SCHEMBL21982380 | 0.77 | — | — | |
| SCHEMBL24049115 | 0.73 | GRIN2C (0.56) | — | |
| SCHEMBL21982383 | 0.70 | — | — | |
| SCHEMBL7904173 | 0.70 | GRIN2C (1.00) | — | |
| SCHEMBL7900368 | 0.70 | GRIN2C (0.93) | — | |
| SCHEMBL7902332 | 0.67 | GRIN2C (0.81) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647679-B2 | N-methyl-D-aspartate receptor (NMDAR) potentiators, pharmaceutical compositions, and uses related thereto | EMORY UNIVERSITY (US) | 2020-05-12 | — | — | US | claimed |
| US-20180244623-A1 | N-methyl-D-aspartate Receptor (NMDAR) Potentiators, Pharmaceutical Compositions, And Uses Related Thereto | UNIV EMORY (US) | 2018-08-30 | — | — | US | claimed |
| WO-2016149248-A1 | N-METHYL-D-ASPARTATE RECEPTOR (NMDAR) POTENTIATORS, PHARMACEUTICAL COMPOSITIONS, AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2016-09-22 | — | — | WO | claimed |