Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.48 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1807792 | 0.89 | EGLN1 (0.54) | EGLN1BBOX1FTOKDM4C | |
| SCHEMBL1819983 | 0.89 | EGLN1 (0.54) | EGLN1BBOX1FTOKDM4C | |
| SCHEMBL1809954 | 0.89 | EGLN1 (0.54) | EGLN1BBOX1FTOKDM4C | |
| SCHEMBL1806922 | 0.88 | EGLN1 (0.46) | EGLN1RAB9ANPC1HSP90AA1PAX8 | |
| SCHEMBL1811891 | 0.82 | EGLN1 (0.72) | EGLN1BBOX1FTO | |
| SCHEMBL1810525 | 0.80 | EGLN1 (0.46) | EGLN1BBOX1FTOKDM4CMEN1 | |
| SCHEMBL1810514 | 0.80 | EGLN1 (0.46) | EGLN1BBOX1FTOKDM4CMEN1 | |
| SCHEMBL1811644 | 0.79 | EGLN1 (0.45) | EGLN1BBOX1FTORAB9ANPC1 | |
| SCHEMBL1809817 | 0.77 | EGLN1 (0.46) | EGLN1BBOX1FTOKDM4CMEN1 | |
| SCHEMBL1809823 | 0.77 | EGLN1 (0.46) | EGLN1BBOX1FTOKDM4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |