Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 19/20 | 0.83 |
| ▸ | VEGFA | P15692 | 9/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | ARNT | P27540 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18078560 | 1.00 | EPAS1 (0.83) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL29426414 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16560907 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16560855 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16560911 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL17683524 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL16560867 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL17671107 | 0.91 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL18036909 | 0.83 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 | |
| SCHEMBL18036908 | 0.83 | EPAS1 (1.00) | EPAS1VEGFACYP2C9ARNTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016145045-A1 | COMPOSITIONS FOR USE IN TREATING GLIOBLASTOMA | PELOTON THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | WO | disclosed |