SCHEMBL18078701

SCHEMBL18078701

c1ccc(-c2ccc(-c3cccs3)nc2)nc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.49
RAB9A P51151 6/20 0.49
SMN1; SMN2 Q16637 6/20 0.49
TP53 P04637 2/20 0.49
MAPT P10636 5/20 0.47
KDM4E B2RXH2 5/20 0.47
GLA P06280 2/20 0.47
CYP2A6 P11509 2/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GAA P10253 3/20 0.45
HSD17B10 Q99714 2/20 0.45
CASP1 P29466 1/20 0.45
MAPK10 P53779 1/20 0.45
CASP7 P55210 1/20 0.45
HPGDS O60760 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18078699 0.90 SMN1; SMN2 (0.51) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL30596386 0.86 KDM4E (0.61) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL36011 0.86 KDM4E (0.61) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL5013752 0.84 KDM4E (0.59) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL10408880 0.84 KDM4E (0.52) NPC1RAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL29778652 0.84 KDM4E (0.59) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL3829194 0.84 KDM4E (0.59) NPC1RAB9ASMN1; SMN2TP53MAPT
Hydrochloric Acid SCHEMBL12004262 0.84 KDM4E (0.59) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL12727899 0.84 KDM4E (0.52) NPC1RAB9ASMN1; SMN2MAPTKDM4E
SCHEMBL30021698 0.84 KDM4E (0.59) NPC1RAB9ASMN1; SMN2TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016143823-A1 COMPOUND, AND ORGANIC SEMICONDUCTOR MATERIAL CONTAINING SAME 国立大学法人大阪大学 2016-09-15 WO disclosed