Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135385 | 1.00 | SLC7A5 (0.43) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL9630785 | 0.83 | TAAR1 (0.46) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL8593961 | 0.83 | SLC7A5 (0.46) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL12154596 | 0.83 | TAAR1 (0.46) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL4541734 | 0.83 | TAAR1 (0.46) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL20133446 | 0.82 | ACE (0.55) | TAAR1ACECAPN1 | |
| SCHEMBL15855461 | 0.81 | CA12 (0.42) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL16168228 | 0.80 | ACE (0.50) | ACECAPN1 | |
| SCHEMBL22112308 | 0.80 | TAAR1 (0.47) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL12703579 | 0.80 | ACE (0.43) | SLC7A5TAAR1SLC6A2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9446139-B2 | Polymer-based compositions and conjugates of HIV entry inhibitors | NEKTAR THERAPEUTICS (US) | 2016-09-20 | — | — | US | disclosed |