Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079697 | 0.86 | SYK (0.36) | AAK1 | |
| SCHEMBL17902791 | 0.85 | AAK1 (0.36) | AAK1 | |
| SCHEMBL16256930 | 0.84 | AAK1 (0.35) | AAK1 | |
| SCHEMBL895372 | 0.83 | AAK1 (0.34) | AAK1 | |
| SCHEMBL17902811 | 0.83 | AAK1 (0.36) | AAK1 | |
| SCHEMBL894455 | 0.81 | AAK1 (0.35) | AAK1 | |
| SCHEMBL17902797 | 0.80 | AAK1 (0.34) | AAK1 | |
| SCHEMBL895099 | 0.78 | AAK1 (0.36) | AAK1 | |
| SCHEMBL895097 | 0.78 | AAK1 (0.36) | AAK1 | |
| SCHEMBL17902793 | 0.78 | CA12 (0.38) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447122-B2 | Arginase inhibitors and methods of use thereof | ASTRAZENECA AB (SE) | 2016-09-20 | — | — | US | disclosed |