⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660048 | 0.77 | — | — | |
| SCHEMBL486558 | 0.74 | — | — | |
| SCHEMBL7001989 | 0.72 | — | — | |
| SCHEMBL1807056 | 0.72 | — | — | |
| SCHEMBL6943514 | 0.72 | — | — | |
| SCHEMBL29349499 | 0.71 | — | — | |
| SCHEMBL22730 | 0.71 | — | — | |
| SCHEMBL8873179 | 0.71 | TP53 (1.00) | — | |
| SCHEMBL11661765 | 0.69 | TP53 (0.93) | — | |
| SCHEMBL5318805 | 0.69 | TP53 (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116019794-A | Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs | 中国科学院化学研究所 | 2023-04-28 | — | — | CN | claimed |
| EP-1607396-A1 | Bicyclic inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION (US) | 2005-12-21 | — | — | EP | claimed |
| EP-1240168-B1 | BICYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORP (US) | 2005-08-31 | — | — | EP | claimed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| US-6800632-B2 | FOR TREATMENT OF DISORDERS MEDIATED BY GSK3 ACTIVITY, SUCH AS DIABETES, ALZHEIMER'S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS, OBESITY, ATHEROSCLEROTIC CARDIOVASCULAR DISEASE | CHIRON CORPORATION | 2004-10-05 | — | — | US | claimed |
| EP-1219594-B1 | New esters derived from substituted phenyl-cyclohexyl compounds | VITA LAB (ES) | 2004-01-14 | — | — | EP | claimed |
| US-20030100598-A1 | Novel esters derived from (rr,ss)-2-hydroxybenzoate of 3-(2-dimethylaminomethyl-1-hydroxycyclohexyl)phenyl | LABORATORIOS VITA, S.A. (ES) | 2003-05-29 | — | — | US | claimed |
| US-20030008866-A1 | Bicyclic inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION | 2003-01-09 | — | — | US | claimed |
| US-6455585-B1 | HAVE A HIGHER ANALGESIC ACTIVITY, A LOWER TOXICITY AND A LONGER EFFECTIVE TIME PERIOD THAN TRAMADOL. | VITA INVEST, S.A. (ES) | 2002-09-24 | — | — | US | claimed |
| EP-1240168-A1 | BICYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-09-18 | — | — | EP | claimed |
| EP-1219594-A1 | New esters derived from substituted phenyl-cyclohexyl compounds | VITA-INVEST, S.A. (ES) | 2002-07-03 | — | — | EP | claimed |
| US-20010044436-A1 | Bicyclic inhibitors of glycogen synthase kinase 3 | CHIRON CORPORATION | 2001-11-22 | — | — | US | claimed |
| EP-1127871-A1 | NEW ESTERS DERIVED FROM SUBSTITUTED PHENYL-CYCLOHEXYL COMPOUNDS | VITA-INVEST, S.A. (ES) | 2001-08-29 | — | — | EP | claimed |
| WO-2001044246-A1 | BICYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2001-06-21 | — | — | WO | claimed |
| EP-1075261-A1 | MYCOBACTERIAL INHIBITORS | AstraZeneca AB (SE) | 2001-02-14 | — | — | EP | claimed |
| WO-1999065483-A1 | MYCOBACTERIAL INHIBITORS | ASTRAZENECA AB (SE) | 1999-12-23 | — | — | WO | claimed |
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| EP-1957073-B1 | MEDICINAL DRUG | OTSUKA PHARMA CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-4148805-A | POLYESTERS, RED, YELLLOW | CIBA-GEIGY AG (CH) | 1979-04-10 | — | — | US | disclosed |
| US-4146541-A | YELLOW SHADE ON POLYESTERS | CIBA-GEIGY AG (CH) | 1979-03-27 | — | — | US | disclosed |