Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18082003 | 1.00 | HDAC1 (0.44) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL7917993 | 0.91 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL7921019 | 0.89 | HDAC1 (0.43) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL7917416 | 0.89 | HDAC1 (0.43) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12104176 | 0.82 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3581644 | 0.80 | KMT2A (0.41) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL2364444 | 0.80 | KMT2A (0.41) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL2354639 | 0.79 | KMT2A (0.42) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3692466 | 0.78 | MEN1 (0.36) | MEN1HPGDKMT2ANPSR1 | |
| SCHEMBL3568621 | 0.78 | KMT2A (0.43) | MEN1HPGDKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46144-E1 | Hydroxamic acid derivatives | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2016-09-13 | — | — | US | disclosed |