Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771033 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL27056171 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL6565769 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL6714473 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL9002482 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL24461133 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL11309058 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL25970344 | 0.97 | TSHR (0.67) | TSHRLMNAALDH1A1KDM4ERECQL | |
| SCHEMBL1327137 | 0.95 | TSHR (0.79) | TSHRLMNAALDH1A1KDM4ERECQL | |
| Hydrochloric Acid SCHEMBL27899274 | 0.92 | TSHR (0.75) | TSHRLMNAALDH1A1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | claimed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | claimed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | claimed |
| WO-2019217890-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2019-11-14 | — | — | WO | disclosed |
| WO-2017015496-A1 | METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2017-01-26 | — | — | WO | disclosed |
| WO-2017004026-A1 | ANTI-CD 123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | IMMUNOGEN, INC. (US) | 2017-01-05 | — | — | WO | disclosed |
| WO-2016036794-A1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN, INC. (US) | 2016-03-10 | — | — | WO | disclosed |
| WO-2016036801-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2016-03-10 | — | — | WO | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2005019212-A1 | COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0746544-A1 | NOVEL INDOLE DERIVATIVES USEFUL TO TREAT ESTROGEN-RELATED NEOPLASMS AND DISORDERS | MERRELL PHARMACEUTICALS INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022524-A1 | NOVEL INDOLE DERIVATIVES USEFUL TO TREAT ESTROGEN-RELATED NEOPLASMS AND DISORDERS | MERRELL PHARMACEUTICALS INC. (US) | 1995-08-24 | — | — | WO | disclosed |
| EP-0001914-B1 | ANTIBACTERIALLY ACTIVE AMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID AMIDES | BEECHAM GROUP PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
| US-4200635-A | MONIC ACID A AMIDES | BEECHAM GROUP LIMITED (GB) | 1980-04-29 | — | — | US | disclosed |
| EP-0001914-A2 | Antibacterially active amides, process for their preparation and pharmaceutical compositions containing said amides | BEECHAM GROUP PLC (GB) | 1979-05-16 | — | — | EP | disclosed |