Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.62 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 4/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809219 | 0.87 | EGLN1 (0.68) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1270194 | 0.85 | EGLN1 (0.69) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1811870 | 0.84 | EGLN1 (0.47) | EGLN1BBOX1FTO | |
| SCHEMBL1811865 | 0.84 | EGLN1 (0.47) | EGLN1BBOX1FTO | |
| SCHEMBL1270012 | 0.80 | EGLN1 (0.73) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1269880 | 0.79 | EGLN1 (0.76) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1811637 | 0.78 | EGLN1 (0.66) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1270563 | 0.78 | EGLN1 (0.67) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1269966 | 0.78 | EGLN1 (0.73) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1270239 | 0.78 | EGLN1 (0.73) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |