SCHEMBL18088456

SCHEMBL18088456

CCCOCCOCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NS)C(C)=O)C(=O)O)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.60
▸ NOD1 Q9Y239 7/20 0.43
▸ FOLH1 Q04609 1/20 0.41
▸ EPHX2 P34913 1/20 0.39
▸ ALB P02768 2/20 0.38
▸ C3AR1 Q16581 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656538 0.90 GLP1R (0.76) GLP1RNOD1EPHX2
SCHEMBL19135689 0.87 GLP1R (0.69) GLP1RNOD1FOLH1
SCHEMBL15002870 0.84 GLP1R (0.57) GLP1RNOD1FOLH1ALBC3AR1
SCHEMBL19069728 0.83 GLP1R (0.55) GLP1RNOD1FOLH1EPHX2C3AR1
SCHEMBL14217277 0.83 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2C3AR1
SCHEMBL14477502 0.83 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2C3AR1
SCHEMBL15358433 0.82 GLP1R (0.66) GLP1RNOD1
SCHEMBL18211313 0.82 GLP1R (0.63) GLP1RNOD1
SCHEMBL15267729 0.82 GLP1R (0.59) GLP1RNOD1
SCHEMBL14998186 0.82 GLP1R (0.57) GLP1RNOD1FOLH1EPHX2C3AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160271263-A1 Acylated Glucagon Analogues NOVO NORDISK AS (DK) 2016-09-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160271263-A1 Acylated Glucagon Analogues GLP1R, GCG, IAPP GLP1R 1/4885NOD1 2294/4885FOLH1 352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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