SCHEMBL1809159

SCHEMBL1809159

CCN(CC)c1ccc(C=Cc2cc3cc(I)ccc3o2)cc1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 18/20 0.74
PRMT1 Q99873 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1809157 1.00 APP (0.74) APPPRMT1
SCHEMBL1807047 0.86 APP (0.74) APPPRMT1
SCHEMBL1807048 0.86 APP (0.74) APPPRMT1
SCHEMBL1808028 0.85 APP (1.00) APP
SCHEMBL1808025 0.85 APP (1.00) APP
SCHEMBL1809408 0.85 APP (0.74) APPPRMT1
SCHEMBL1807052 0.85 APP (0.74) APPPRMT1
SCHEMBL1809407 0.85 APP (0.74) APPPRMT1
SCHEMBL1807054 0.85 APP (0.74) APPPRMT1
SCHEMBL1808124 0.84 APP (0.75) APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110124888-A1 STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2011-05-26 US claimed
US-20110124888-A1 STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2011-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124888-A1 STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF APP, BACE1, PSEN1 APP 1/4885PRMT1 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.