⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18230746 | 0.97 | — | — | |
| SCHEMBL7524303 | 0.67 | — | — | |
| SCHEMBL3212042 | 0.67 | — | — | |
| SCHEMBL14791365 | 0.67 | — | — | |
| SCHEMBL908245 | 0.67 | — | — | |
| SCHEMBL13465286 | 0.67 | — | — | |
| SCHEMBL14223732 | 0.67 | — | — | |
| SCHEMBL7782772 | 0.67 | — | — | |
| SCHEMBL5074927 | 0.65 | — | — | |
| Methane SCHEMBL10339744 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62164677-A | — | — | None | — | — | JP | disclosed |
| US-11730703-B2 | Nanoparticles for treatment of posterior segment ocular diseases and conditions | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-08-22 | — | — | US | disclosed |
| CN-102471315-B | Novel method for producing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG | 2014-05-28 | — | — | CN | disclosed |
| EP-2021344-B1 | BICYCLIC ENAMINO(THIO)CARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-05-08 | — | — | EP | disclosed |
| EP-2467374-B1 | New method for manufacturing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2467374-B1 | New method for manufacturing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-8314242-B2 | Process for the preparation of 4-aminobut-2-enolides | BayerCrop Science AG (DE) | 2012-11-20 | — | — | US | disclosed |
| EP-2467374-A1 | NOVEL METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-7951951-B2 | Bicyclic enamino(thio)carbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2011-05-31 | — | — | US | disclosed |
| US-20110054182-A1 | Novel Process for the Preparation of 4-Aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2011-03-03 | — | — | US | disclosed |
| EP-0863890-A1 | 5-AMIDOMETHYL ALPHA, BETHA-SATURATED AND -UNSATURATED 3-ARYL BUTYROLACTONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5708169-A | BACTERICIDES FOR TREATMENT OF GRAM POSITIVE INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| WO-1997010235-A1 | 5-AMIDOMETHYL α, β-SATURATED AND -UNSATURATED 3-ARYL BUTYROLACTONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-20 | — | — | WO | disclosed |
| US-5441974-A | Phenyl amidines lactones useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-08-15 | — | — | US | disclosed |
| US-5232944-A | Hypotensive agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-03 | — | — | US | disclosed |
| WO-1993012103-A1 | PHENYL AMIDINES LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1993-06-24 | — | — | WO | disclosed |
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |
| EP-0422450-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-04-17 | — | — | EP | disclosed |
| JP-S62164677-A | PRODUCTION OF 4-HYDROXY-2(5H)-FURANONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1987-07-21 | — | — | JP | disclosed |
| EP-0111453-A1 | Amide derivatives | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |