⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645287 | 0.74 | — | — | |
| SCHEMBL28827769 | 0.64 | HSP90AA1 (0.33) | — | |
| SCHEMBL927156 | 0.62 | — | — | |
| SCHEMBL1866401 | 0.61 | — | — | |
| SCHEMBL28420034 | 0.60 | — | — | |
| SCHEMBL4067146 | 0.60 | — | — | |
| Ethyne SCHEMBL28058284 | 0.60 | — | — | |
| SCHEMBL7215900 | 0.59 | NISCH (0.37) | — | |
| SCHEMBL27591106 | 0.58 | — | — | |
| SCHEMBL6418743 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473283-B2 | Compounds and their use | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2025-11-18 | — | — | US | disclosed |
| US-20240317740-A1 | NOVEL COMPOUNDS AND THEIR USE | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2024-09-26 | — | — | US | disclosed |
| CN-103857681-B | It is used as the new big ring of factor XI, plasma thromboplastin antecedent A inhibitor | 百时美施贵宝公司 | 2017-07-14 | — | — | CN | disclosed |
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. | 2017-06-08 | — | — | US | disclosed |
| WO-2017043636-A1 | NOVEL BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE OF SAME | 大日本住友製薬株式会社 | 2017-03-16 | — | — | WO | disclosed |
| EP-2493888-A1 | BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS | Sirtris Pharmaceuticals, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011059839-A1 | BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| EP-0804440-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |
| US-4029667-A | Certain 1-carbothioamides of 1,8-naphthyridines, pyrrolo(2,3-b)pyridines and pyrido(2,3-b)azepines | JOHN WYETH & BROTHER LIMITED (EN) | 1977-06-14 | — | — | US | disclosed |
| US-3960876-A | Certain 1-carbothioamides of 1,8-naphthyridines, pyrrolo(2,3-b)pyridines and pyrido(2,3-b)azepines | JOHN WYETH & BROTHER, LTD. (EN) | 1976-06-01 | — | — | US | disclosed |