SCHEMBL18095965

SCHEMBL18095965

[c]1cc2c(s1)COC=C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21555681 0.54
SCHEMBL10621257 0.54
SCHEMBL15902739 0.54 PARP1 (0.39)
SCHEMBL31129123 0.52
SCHEMBL655807 0.52
SCHEMBL655806 0.52
SCHEMBL20787073 0.49
SCHEMBL11268963 0.48
SCHEMBL318474 0.48
SCHEMBL10595589 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059107-A1 IKZF2 AND CK1-ALPHA DEGRADING COMPOUNDS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-03-21 WO disclosed
EP-3277701-A1 SYNTHESIS OF DESOSAMINES President and Fellows of Harvard College (US) 2018-02-07 EP disclosed
WO-2016154533-A1 SYNTHESIS OF DESOSAMINES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-09-29 WO disclosed