Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.94 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18096704 | 0.97 | SCN9A (1.00) | SCN9ASCN5AAKT1 | |
| SCHEMBL20481741 | 0.95 | SCN9A (0.85) | SCN9ASCN5AAKT1ALOX5APFEN1 | |
| SCHEMBL18096618 | 0.89 | SCN9A (0.74) | SCN9ASCN5AALOX5APFEN1 | |
| SCHEMBL18096708 | 0.82 | SCN9A (0.84) | SCN9ASCN5AALOX5APFEN1 | |
| SCHEMBL18096752 | 0.81 | SCN9A (1.00) | SCN9ASCN5AAKT1 | |
| SCHEMBL18096762 | 0.80 | SCN9A (0.84) | SCN9ASCN5A | |
| SCHEMBL20481820 | 0.80 | SCN9A (0.78) | SCN9ASCN5AAKT1 | |
| SCHEMBL20481949 | 0.80 | SCN9A (0.70) | SCN9ASCN5AAKT1ALOX5APFEN1 | |
| SCHEMBL18096718 | 0.80 | SCN9A (0.62) | SCN9ASCN5AALOX5APFEN1 | |
| SCHEMBL18096607 | 0.79 | SCN9A (1.00) | SCN9ASCN5AAKT1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274335-A1 | AMINOINDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | Almirall S.A. (ES) | 2018-01-31 | — | — | EP | claimed |
| WO-2016150971-A1 | AMINOINDAZOLE DERIVATIVES AS SODIUM CHANNEL INHIBITORS | ALMIRALL, S.A. (ES) | 2016-09-29 | — | — | WO | claimed |