Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.67 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810773 | 0.84 | EGLN1 (0.71) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1269880 | 0.81 | EGLN1 (0.76) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1269131 | 0.81 | EGLN1 (1.00) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1270239 | 0.79 | EGLN1 (0.73) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1270012 | 0.79 | EGLN1 (0.73) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1270251 | 0.79 | EGLN1 (0.76) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1809219 | 0.78 | EGLN1 (0.68) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1268876 | 0.78 | EGLN1 (0.71) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL1269966 | 0.77 | EGLN1 (0.73) | EGLN1FTOBBOX1THRATHRB | |
| SCHEMBL23493314 | 0.77 | EGLN1 (0.65) | EGLN1FTOBBOX1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |