Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.69 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811321 | 0.84 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1270342 | 0.82 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1810525 | 0.81 | EGLN1 (0.46) | EGLN1BBOX1FTO | |
| SCHEMBL1810514 | 0.81 | EGLN1 (0.46) | EGLN1BBOX1FTO | |
| SCHEMBL1814831 | 0.81 | EGLN1 (0.69) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1811976 | 0.79 | EGLN1 (0.69) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1811891 | 0.79 | EGLN1 (0.72) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1270138 | 0.78 | EGLN1 (0.74) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1811637 | 0.78 | EGLN1 (0.66) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL967787 | 0.75 | EGLN1 (0.60) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |