Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ABL1 | P00519 | 3/20 | 0.64 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145933 | 0.88 | TDP1 (0.72) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL18106287 | 0.84 | TDP1 (0.58) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL18106282 | 0.81 | TDP1 (0.64) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL18106301 | 0.78 | TDP1 (0.70) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL924239 | 0.76 | TDP1 (0.58) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL18106267 | 0.76 | TDP1 (0.58) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL192058 | 0.76 | TDP1 (0.68) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL723098 | 0.72 | TDP1 (0.57) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL5133361 | 0.72 | TDP1 (0.53) | TDP1ABL1RIN1KDM4EKMT2A | |
| SCHEMBL725117 | 0.69 | TDP1 (0.54) | TDP1ABL1RIN1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3075736-B1 | MERCAPTOALKYL GLYCOLURILS AND USE OF SAME | SHIKOKU CHEM (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-10030023-B2 | Mercaptoalkylglycolurils and use of same | SHIKOKU CHEMICALS CORPORATION (JP) | 2018-07-24 | — | — | US | disclosed |
| US-20160289237-A1 | MERCAPTOALKYLGLYCOLURILS AND USE OF SAME | SHIKOKU CHEMICALS CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3075736-A1 | MERCAPTOALKYL GLYCOLURILS AND USE OF SAME | Shikoku Chemicals Corporation (JP) | 2016-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289237-A1 | MERCAPTOALKYLGLYCOLURILS AND USE OF SAME | CYSLTR1, MGMT, CYSLTR2 | TDP1 4571/4885ABL1 951/4885RIN1 2207/4885 |
| US-10030023-B2 | Mercaptoalkylglycolurils and use of same | CYSLTR1, MGMT, CYSLTR2 | TDP1 4571/4885ABL1 951/4885RIN1 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.