Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 8/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720347 | 0.93 | FASN (0.44) | FASNGSK3BACACAMETOPRM1 | |
| SCHEMBL14720559 | 0.93 | FASN (0.43) | FASNGSK3BACACAMETOPRM1 | |
| SCHEMBL14720219 | 0.87 | FASN (0.45) | FASNGSK3BACACAMETOPRM1 | |
| SCHEMBL14720427 | 0.86 | FASN (0.61) | FASNGSK3BACACAHSD17B1HSD17B2 | |
| SCHEMBL14720259 | 0.83 | FASN (0.39) | FASN | |
| SCHEMBL14720149 | 0.82 | FASN (0.38) | FASN | |
| SCHEMBL14720304 | 0.82 | FASN (0.35) | FASNKDM1A | |
| SCHEMBL14720244 | 0.81 | FASN (0.38) | FASN | |
| SCHEMBL15581999 | 0.81 | FASN (0.47) | FASNOPRM1CHRM1 | |
| SCHEMBL14720281 | 0.81 | FASN (0.37) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744333-B1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-10-05 | — | — | EP | claimed |