Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 4/20 | 0.46 |
| ▸ | HPGDS | O60760 | 4/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720251 | 0.94 | FASN (0.46) | FASNHPGDSNPY5RGSK3BDYRK1A | |
| SCHEMBL14720204 | 0.94 | FASN (0.45) | FASNHPGDSNPY5RKCNJ1 | |
| SCHEMBL14720427 | 0.87 | FASN (0.61) | FASNNPY5RGSK3B | |
| SCHEMBL14720307 | 0.85 | FASN (0.46) | FASNNPY5R | |
| SCHEMBL14720369 | 0.85 | FASN (0.47) | FASNNPY5R | |
| SCHEMBL14720418 | 0.83 | FASN (0.59) | FASNNPY5RGSK3B | |
| SCHEMBL14720316 | 0.83 | FASN (0.46) | FASNNPY5R | |
| SCHEMBL15543128 | 0.82 | FASN (0.48) | FASN | |
| SCHEMBL15543454 | 0.82 | FASN (0.48) | FASN | |
| SCHEMBL14720197 | 0.82 | FASN (0.45) | FASNNPY5RKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2744333-B1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2016-10-05 | — | — | EP | claimed |