Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106933 | 1.00 | S1PR1 (0.77) | S1PR1 | |
| SCHEMBL773309 | 0.87 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL773308 | 0.87 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL773373 | 0.87 | S1PR1 (0.77) | S1PR1 | |
| SCHEMBL773350 | 0.85 | S1PR1 (0.87) | S1PR1 | |
| SCHEMBL773349 | 0.85 | S1PR1 (0.87) | S1PR1 | |
| SCHEMBL772674 | 0.85 | S1PR1 (0.75) | S1PR1 | |
| SCHEMBL798129 | 0.83 | S1PR1 (1.00) | S1PR1 | |
| SCHEMBL771863 | 0.82 | S1PR1 (0.80) | S1PR1 | |
| SCHEMBL797686 | 0.81 | S1PR1 (1.00) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440554-B1 | PYRAZOLE OXADIAZOLE DERIVATIVES AS S1P1 AGONISTS | MERCK SERONO SA (CH) | 2016-10-05 | — | — | EP | disclosed |