Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27995853 | 0.97 | PIK3CD (0.46) | PIK3CDMEN1KMT2AMAPTATM | |
| SCHEMBL101925 | 0.97 | — | — | |
| SCHEMBL4924066 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL28006932 | 0.95 | MEN1 (0.50) | PIK3CDMEN1KMT2AMAPTATM | |
| SCHEMBL426509 | 0.94 | MEN1 (0.55) | PIK3CDMEN1KMT2AMAPTATM | |
| Iodide SCHEMBL31035714 | 0.94 | PIK3CD (0.48) | PIK3CDMEN1KMT2AMAPTATM | |
| SCHEMBL425336 | 0.94 | MEN1 (0.55) | PIK3CDMEN1KMT2AMAPTATM | |
| SCHEMBL19969742 | 0.94 | MEN1 (0.55) | PIK3CDMEN1KMT2AMAPTATM | |
| Hydrochloric Acid SCHEMBL28126144 | 0.94 | PIK3CD (0.48) | PIK3CDMEN1KMT2AMAPTATM | |
| SCHEMBL13635633 | 0.94 | MEN1 (0.55) | PIK3CDMEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275107-B1 | Combinations for the treatment of diseases involving cell proliferation | BOEHRINGER INGELHEIM INT (DE) | 2016-10-05 | — | — | EP | disclosed |